Receptors Related to Innate Immunity

Unlike the receptors that mediate adaptive immunity, the receptors of the innate immunity are typically not clonally distributed; a given set of receptors will be present on all the cells of the same cell type. The binding of pathogens by these receptors gives rise to very rapid responses, which are put into effect without the delay imposed by the clonal expansion of cells needed in the adaptive immune response.

The innate immunity related cells including: NK cells, mast cells, monocytes and dendritic cells, and function within the immune system by identifying and eliminating pathogens that might cause infection. The innate immunity recognizes such pathogens by means of receptors that bind features of these regular patterns; these receptors are sometimes known as pattern-recognition molecules. The innate immunity receptors that recognize pathogens also have an important role in signaling for the induced responses responsible for local inflammation, the recruitment of new effector cells, the containment of local infection, and the initiation of an adaptive immune response.

Receptors Related to Innate Immunity

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TRA2A CD16a/Fc gamma  RIIIa CD16b/Fc gamma  RIIIb
CD16-2/FCGR4 CD32a/FCGR2A/Fc gamma RIIA CD32b/FCGR2B/Fc gamma RIIB
TRA2B C5AR1/C5R1/CD88 G-CSF R/CD114/CSF3R
IL6R/IL-6R/CD126 CD155/PVR KIR2DL4 / CD158D
CD180/RP105 CCR2 CCR4/CD194
CCR5 CCR8 IL13RA1/IL-13RA1
IL18R1 IL18RAP TLR1 / CD281
TLR2 (CD282) TLR3 / CD283 TLR4 / TLR-4
TLR6 TLR10 CSF2RA
CX3CR1 CXCR4/CD184 EGFR/HER1
FPR3 IL-1RA/IL1RN IL-1RAcP/IL-1R3
TNFR1/TNFRSF1A/CD120a TNFR2/TNFRSF1B/CD120b TRAF3 / CD40BP
TRAF3IP1
Receptors
Receptors Classification
Receptors by Differentiation Cells
Receptors by Functions
Receptors Related to Innate Immunity
Receptors Related to Cell Activation
Receptors Related to CD Antigens
Receptors Related to Cell Adhesion
Receptors Related to Signaling Pathways
Receptors Reagent Products
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