SAPK4 (Protein|Antibody|cDNA Clone|ELISA Kit)

All SAPK4 reagents are produced in house and quality controlled, including 2 SAPK4 Antibody, 30 SAPK4 Gene, 1 SAPK4 IPKit, 2 SAPK4 Lysate, 2 SAPK4 Protein, 2 SAPK4 qPCR. All SAPK4 reagents are ready to use.

Recombinant SAPK4 proteins are expressed by Baculovirus-Insect cells with fusion tags as N-GST.

SAPK4antibodies are validated with different applications, which are ELISA, WB, IP.

SAPK4cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each SAPK4 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

SAPK4 Protein (2)

Species

SAPK4 Protein, Human, Recombinant (GST Tag)

10747-H09B

Expression host: Baculovirus-Insect Cells

Human p38 delta/MAPK13 Protein 9082

SAPK4 Protein, Human, Recombinant (GST Tag), Activated in vitro

10747-H09B-A

Expression host: Baculovirus-Insect cells

Human p38 delta/MAPK13 Protein 9083
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SAPK4 Antibody (2)

Application Clonality
Host

Anti-SAPK4 Antibody

10747-RP01

Application: ELISA

Clonality: PAb

Anti-SAPK4 Antibody

10747-T52

Application: WB,ELISA,IP

Clonality: PAb

Human p38 delta/MAPK13 Immunoprecipitation(IP) 6171
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SAPK4 cDNA Clone (30)

Mouse
Human

SAPK4 qPCR Primer (2)

SAPK4 IP Kit (1)

SAPK4 Lysate (2)

The p38 family of mitogen-activated protein kinases (MAPK) includes p38 alpha (SAPK2a, CSBP), p38 beta (SAPK2b), p38 delta (SAPK4), and p38 gamma (SAPK3/ERK6). p38 alpha and p38 beta are widely expressed p38 isoforms that are involved in regulation of cell proliferation, differentiation, development, and response to stress. p38 delta, also known as MAPK13, is a regulator of differentiation-dependent gene expression in keratinocytes, and been as a regulator of surface epithelia differentiation and apoptosis. p38 delta protein is upregulated in Cholangiocarcinoma (CC) relative to hepatocellularcarcinoma (HCC) and to normal biliary tract tissues. p38 delta is important for motility and invasion of CC cells, suggesting that p38 delta may play an important role in CC metastasis. p38 delta is expressed in the epidermis, suggesting a role for p38 delta in regulating differentiation. p38 delta is the major p38 isoform driving suprabasal involucrin gene expression and that p38 delta directly regulates ERK1/2 activity via formation of a p38 delta-ERK1/2 complex. Recent emerging evidence suggests that the p38 stress MAPK pathway may function as a tumor suppressor through regulating Ras-dependent and -independent proliferation, transformation, invasion and cell death by isoform-specific mechanisms. p38 delta has important role in promoting cell proliferation and tumor development in epidermis and may have therapeutic implication for skin cancer.

Protein
Antibody
Gene
qPCR
IPKit
Lysate
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