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Mouse CD23/FCER2 Protein, Antibody, Gene cDNA Clone & ELISA Kit

Product NameMoleculeSpeciesCat No.PackagePrice 
Mouse CD23 / FCER2 Protein (His Tag)CD23/FCER2Mouse
50 µg
100 µg
Product NameApplication(key)Reactivity(key)Cat No.PackagePrice 
CD23 / FCER2 Antibody (FITC), Rabbit MAbFCM  Mouse
50 Tests
100 Tests
CD23 / FCER2 Antibody (PE), Rabbit MAbFCM  Mouse
50 Tests
100 Tests
CD23 / FCER2 Antibody (APC), Rabbit MAbFCM  Mouse
50 Tests
100 Tests
CD23 / FCER2 Antibody (PerCP), Rabbit MAbFCM  Mouse
50 Tests
100 Tests
CD23 / FCER2 Antibody, Rabbit MAbELISA  Mouse
50 µg
100 µg
CD23 / FCER2 Antibody, Rabbit PAbELISA  Mouse
400 µg
200 µg
100 µg
CD23 / FCER2 Antibody, Rabbit PAb, Antigen Affinity PurifiedELISA  Mouse
50 µg
200 µg
100 µg

Additional Mouse Fc Receptor Products

Additional Specie Products of Fc Receptor

Mouse Fc Receptor FCER2 Background

Fc fragment of IgE, low affinity II, receptor for (CD23) or CD23 antigen is a member of the cluster of differentiation family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD23/FCER2 is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Increased levels of soluble CD23/FCER2 cause the recruitment of non-sensitised B-cells in the presentation of antigen peptides to allergen-specific B-cells, therefore increasing the production of allergen specific IgE. IgE, in turn, is known to upregulate the cellular expression of CD23 and Fc epsilon RI (high-affinity IgE receptor).

Mouse Fc Receptor CD23/FCER2 Reference

  • Aubry JP, et al. (1992) CD21 is a ligand for CD23 and regulates IgE production. Nature. 358(6386): 505-7.
  • Punnonen J, et al. (1993) Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci U S A. 90(8): 3730-4.
  • Yu P, et al. (1994) Negative feedback regulation of IgE synthesis by murine CD23. Nature. 369(6483): 753-6.
  • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"