MCP2 cDNA Clone: Expression and Clone Vector / Plasmid

MCP2 cDNA / Gene Overview

CCL8 gene / cDNA is a protein-coding gene which located on 17q12. The CCL8 gene is conserved in chimpanzee, Rhesus monkey, dog, and cow.43 organisms have orthologs with human gene CCL8.

MCP2 cDNA / Gene Function

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014]

MCP2 cDNA / Gene Sequence

LOCUS
LOCUS NM_005623 1351 bp mRNA linear PRI 11-AUG-2018
DEFINITION
Homo sapiens C-C motif chemokine ligand 8 (CCL8), mRNA.
ACCESSION
NM_005623
VERSION
NM_005623.2

This sequence information is just for reference only.

MCP2 Family & Reagents

MCP2 Gene family reagents (Chemokine ligands)

Approved Symbol Reagent list
CCL24
CXCL1
CCL23
CCL16
CXCL10
CCL18
CCL3
CCL1
CXCL12
CXCL16
Approved Symbol Reagent list
XCL1
CCL21
CCL7
CCL27
XCL2
CCL20
CCL11
CXCL14
CXCL8
CXCL11

MCP2 Gene family reagents (Endogenous ligands)

Approved Symbol Reagent list
CALM2
PSAP
CCL2
NCR3LG1
GH1
C5
CCL17
VIP
FGG
APP
Approved Symbol Reagent list
CD274
Fgf8
CXCL10
GAL
CNTN1
CALCB
IL1A
MMP1
CXCL1
CCL11

MCP2 cDNA / Gene Alias

  • HC14
  • MCP-2

MCP2 cDNA / Gene Expression

Broad expression in small intestine (RPKM 5.2), fat (RPKM 4.6) and 22 other tissues