MAG cDNA Clone: Expression and Clone Vector / Plasmid

MAG cDNA / Gene Overview

MAG gene / cDNA is a protein-coding gene which located on 19q13.1. The MAG gene is conserved in Rhesus monkey, dog, cow, mouse, rat, zebrafish, and frog.156 organisms have orthologs with human gene MAG.

MAG cDNA / Gene Function

The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010]

MAG cDNA / Gene Sequence

LOCUS
LOCUS NM_080600 2503 bp mRNA linear PRI 25-JUN-2018
DEFINITION
Homo sapiens myelin associated glycoprotein (MAG), transcript variant 2, mRNA.
ACCESSION
NM_080600 XM_005258947
VERSION
NM_080600.2

This sequence information is just for reference only.

MAG Family & Reagents

MAG Gene family reagents (C2-set domain containing)

Approved Symbol Reagent list
VCAM1
SIGLEC10
CADM1
CD22
MCAM
KIRREL2
CD2
BTN3A1
CD274
CD200R1
Approved Symbol Reagent list
NECTIN1
CADM3
KIRREL3
CADM2
CADM4
BCAM
CD80
KIRREL1
ICOSLG
CD276

MAG Gene family reagents (I-set domain containing)

Approved Symbol Reagent list
ROBO4
IL1R1
NRG2
WFIKKN2
CLMP
TMIGD1
CNTN6
UNC5A
NPTN
CHL1
Approved Symbol Reagent list
KIRREL1
JAM2
LRIG1
NRG1
CEACAM5
NEGR1
NFASC
HepaCAM2
CNTN5
VCAM1

MAG Gene family reagents (Sialic acid binding Ig like lectins)

Approved Symbol Reagent list
CD22
SIGLEC10
SIGLEC5
Approved Symbol Reagent list
CD33
SIGLEC15
SIGLEC6

MAG cDNA / Gene Alias

  • sialic acid binding Ig-like lectin 4A
  • SIGLEC4A
  • SIGLEC-4A
  • S-MAG

MAG cDNA / Gene Expression

Biased expression in brain (RPKM 53.6) and ovary (RPKM 16.9)