IL2 cDNA Clone: Expression and Clone Vector / Plasmid

IL2 cDNA / Gene Overview

IL2 gene / cDNA is a protein-coding gene which located on 4q27. The IL2 gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, and rat.112 organisms have orthologs with human gene IL2.

IL2 cDNA / Gene Function

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]

IL2 cDNA / Gene Sequence

LOCUS
LOCUS NM_000586 822 bp mRNA linear PRI 12-AUG-2018
DEFINITION
Homo sapiens interleukin 2 (IL2), mRNA.
ACCESSION
NM_000586
VERSION
NM_000586.3

This sequence information is just for reference only.

IL2 Family & Reagents

Gene family

IL2 Gene family reagents (Interleukins)

Approved Symbol Reagent list
IL4
IL23A
IL25
IL10
IL1A
IL21
IL1RN
IL34
IL24
IL1F10
Approved Symbol Reagent list
IL20
IL9
IL15
IL32
IL13
IL7
IL17C
IL3
IL37
IL1B

IL2 cDNA / Gene Alias

  • IL-2
  • T cell growth factor
  • TCGF

IL2 cDNA / Gene Expression

Low expression observed in reference dataset