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Human CD16/Fc gamma RIII Protein, Antibody, Gene cDNA Clone & ELISA Kit

Product NameApplication(key)Reactivity(key)Cat No.PackagePrice 
CD16/Fc gamma RIII Antibody (FITC), Mouse MAbHuman
25 Test
100 Tests
CD16/Fc gamma RIII Antibody (PerCP), Mouse MAbHuman
25 Test
100 Tests
CD16/Fc gamma RIII Antibody (PerCP), Mouse MAbHuman
25 Test
100 Tests
CD16/Fc gamma RIII Antibody (APC), Mouse MAbHuman
25 Test
100 Tests
CD16/Fc gamma RIII Antibody (PE), Mouse MAbHuman
25 Test
100 Tests
CD16/Fc gamma RIII Antibody (FITC), Mouse MAbHuman
25 Test
100 Tests
CD16/Fc gamma RIII Antibody (PerCP), Mouse MAbHuman
25 Test
100 Tests
CD16/Fc gamma RIII Antibody (FITC), Mouse MAbHuman
25 Test
100 Tests
CD16/Fc gamma RIII Antibody (PE), Mouse MAbHuman
25 Test
100 Tests
CD16/Fc gamma RIII Antibody (APC), Mouse MAbHuman
25 Test
100 Tests
CD16 / FCGR3 Antibody, Rabbit MAbFCM  Mouse
50 µg
100 µg
CD16/Fc gamma RIII Antibody (FITC), Rabbit MAbHuman
25 Test
100 Tests
CD16/Fc gamma RIII Antibody, Mouse MAbHuman
50 µg
200 µg
100 µg
CD16/Fc gamma RIII Antibody, Mouse MAbHuman
50 µg
200 µg
100 µg
CD16/Fc gamma RIII Antibody, Rabbit MAbHuman
50 µg
100 µg
CD16/Fc gamma RIII Antibody, Mouse MAbHuman
50 µg
200 µg
100 µg

Additional Human Fc Receptor Products

Additional Specie Products of Fc Receptor

Human Fc Receptor FCGR3 Background

Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.

Human Fc Receptor CD16/Fc gamma RIII Reference

  • Edberg JC, et al. (2002) Genetic linkage and association of Fcgamma receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus. Arthritis Rheum. 46(8): 2132-40.
  • Li P, et al. (2002) Recombinant CD16A-Ig forms a homodimer and cross-blocks the ligand binding functions of neutrophil and monocyte Fcgamma receptors. Mol Immunol. 38(7): 527-38.
  • Li P, et al. (2007) Affinity and kinetic analysis of Fcgamma receptor IIIa (CD16a) binding to IgG ligands. J Biol Chem. 282(9): 6210-21.
  • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"