High-throughput Antibody Production Service

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Antibody Development & Production Service
High-throughput Antibody Production Service+
Mini-scale Antibody Production Service(0.1mg-1mg)
Small-Mid scale Recombinant Antibody Production Service(1mg-100mg)
Large-scale Recombinant Antibody Production Service
Rabbit Monoclonal Antibody Development Service
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Therapeutic Antibody Development Service+
Protein antigen production
Peptide design & synthesis
Mouse monoclonal antibody development
Rabbit monoclonal antibody development
Hybridoma cell culture and antibody production
Monoclonal antibody sequencing
High-throughput antibody production
Antibody Engineering Service+
Chimeric antibody production service
Antibody fragment production service
Bispecific antibody production service
Anti-idiotype antibody development service
Biopharmaceutical Analysis Service
Bioprocess Engineering Service

High-throughput Antibody Production Service Features

Sino Biological has a professional mammalian cell expression platform with more than 10 years of process optimization and production experience, providing one-stop services from gene synthesis to high-quality antibody production. For the past 10 years, Sino Biological has provided thousands of antibodies production service to customers worldwide and has established good cooperation relationships with world's leading pharmaceutical companies. Sino Biological is the preferred antibody production service provider for Top10 pharmaceutical companies worldwide.

High-throughput Antibody Production Service Item

Antibody Production Service

Timeline:2-3 weeks

  • • Free codon optimization
  • • Optimized high-efficiency expression vectors
  • • Optimized culture medium and expression systems
  • • Flexible production scales
  • • Fast turnaround
  • • Great expression capacity: >100 antibodies per week

Small and Mid-scale
Antibody Production Service

Antibody Production Service

Timeline:3-6 weeks

  • • Self-developed high-efficiency culture medium and transfection reagents, high-expression vectors and engineering cell lines with indigenous intellectual property, ensuring high success rates at low cost for antibody production
  • • Different culture scale from shake flasks to bioreactors, 24 hours a day, 7 days a week continuous culturing to ensure rapid production of antibodies
  • • Provide transient transfection for antibody production, and develops stable cell lines for antibodies production to meet different customers needs
  • • Express full-length antibody of each subtype (IgG1, IgG2a, IgG2b, IgG3, IgG4, IgM, etc.), chimeric antibody (human/mouse chimeric antibody, mouse/rabbit chimeric antibody, etc.), and also antibody fragments (Fab, scFv, nanobody, etc.)
  • • Produce antibodies with high-purity, high-concentration and low-endotoxin according to customers demands
  • • One-stop Service: Mab development- Hybridoma antibody gene sequencing - Mouse antibody production - Chimeric antibody production - Antibody humanization - Antibody affinity maturation - Antibody characterization and analysis- Process development - GMP production

High-throughput Antibody Production Service Highlights

Capacity and technology platform
• >20 shakers, >800 bottles culture capacity weekly
• >100 bioreactors (2L~1000L)
• Cell culture capacity: >50,000 L yearly
• Free codon optimization
• Optimized high-efficiency expression vectors
• Optimized proprietary culture medium
• Optimized mammalian cell expression platform
Rich experience
• Experienced in expressing different kinds of antibodies:
scFv antibody, Fab antibody, full length antibody, chimeric antibody, bispecific antibody, multi-chains co-transfection and expression, etc.
• Experienced in expressing and purifying multi-isotypes antibodies:
Human IgG1, IgG2, IgG3, IgG4
Mouse IgG1, IgG2a, IgG2b, IgG3
Rat IgG1, IgG2a, IgG2b, IgG2c
Rabbit IgG
Canine IgG
IgA, IgM, IgE
High quality
• High monomer purity: up to 99.9%
• Low endotoxin level: as low as 0.01 EU/mg
• Comprehensive quality control analysis:
UV, SDS-PAGE, ELISA, qPCR, SEC-HPLC, CEX-HPLC, LC-MS/MS, CE-SDS, ADCC,CDC, OCTET Affinity,  Kinetics,  off-rate, ranking