granzyme H (GZMH)

This enzyme is probably necessary for target cell lysis in cell-mediated immune responses.

Granzyme H (GZMH) Related Areas

Enzyme>>Protease & Regulator>>Serine Protease & Regulator>>Granzyme>>Granzyme H/GZMH

Cancer>>Apoptosis>>Granzyme>>Granzyme H/GZMH

Immunology>>Innate Immunity>>Natural Killer Cell (NK Cell)>>Granzyme H/GZMH

Granzyme H (GZMH) Alternative Names

Granzyme H, GZMH, CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2

Summaries for Granzyme H (GZMH)

Entrez Gene summary for Granzyme H (GZMH):

OMIM - description for Granzyme H (GZMH):

Wikipedia summary for Granzyme H (GZMH):

Granzyme H is a protein that in humans is encoded by the GZMH gene.

Human Granzyme H (GZMH) Protein General Information

 

• Protein names: Recommended name: Granzyme H
• Sequence length: 246 AA.
• Domain: Signal
• Sequence similarities: Belongs to the peptidase S1 family. Granzyme subfamily. Contains 1 peptidase S1 domain.
• Subcellular location: Cytoplasmic granule. Note: Cytoplasmic granules of cytolytic T-lymphocytes.

General information above from UniProt

Function for Granzyme H (GZMH) Protein

UniProtKB:

This enzyme is probably necessary for target cell lysis in cell-mediated immune responses.

Genatlas:

• Granzyme H (GZMH) may be necessary for target cell lysis in cell-mediated immune responses
• Granzyme H (GZMH) is involved in cytolysis
• Granzyme H (GZMH) acts as a serine-type endopeptidase

Homology for human Granzyme H (GZMH)

• homolog to murine Gzmg
• ortholog to rattus Rnkp7