CRO Service Features
Sino Biological Inc. has been offering high quality biological research reagents and comprehensive CRO services for over 10 years to accelerate life science research and biological product development worldwide. Possessing professional scientists and engineers, advanced instrument and equipment, and proprietary technology and optimized process, Sino Biological provides superior and integrated CRO services, including recombinant protein production service, antibody development service and biopharmaceutical service.
Most popular CRO service
- • Over 10 years' experience for 6000+ recombinant proteins production.
- • One-stop service from gene synthesis and vector construction to protein expression and purification.
- • Multiple protein expression systems: bacterial, yeast, baculovirus-insect and mammalian expression system.
- • Multiple purification systems (30+) to choose.
- • High R & D ability with over 1000 new proteins per year and quick problem-solving ability.
- • Close to 100 bioreactors with various volume between 2-1000 L to guarantee high-throughput and large-scale production.
- • professional mammalian cell expression platform with more than 10 years of process optimization and production experience, providing one-stop services from gene synthesis to high-quality antibody production.
- • provided thousands of antibodies production service to customers worldwide and has established good cooperation relationships with world's leading pharmaceutical companies
- • >20 shakers, >800 bottles culture capacity weekly;>100 bioreactors(2L~1000L);Cell culture capacity: >50,000 L yearly
- • provide rapid production of recombinant antibodies ranging from milligrams to kilograms, meeting the high throughput and large-scale production requirements of customers.
- • High monomer purity: up to 99.9%;Low endotoxin level: as low as 0.01 EU/mg
- • Comprehensive quality control analysis: UV, SDS-PAGE, ELISA, qPCR, SEC-HPLC, CEX-HPLC, LC-MS/MS, CE-SDS, ADCC,CDC, OCTET Affinity, Kinetics, off-rate, ranking
CRO service items
- • High-efficiency expression vectors
- • High cell density culturing
- • Proprietary medium formulation
- • >6000 proteins expression and purification experience
- • Inclusion body refolding & soluble expression
- • Protein biopharmaceutical technology
- • Hybridoma & phage display library technology
- • Multiple validation platforms: ELISA, IHC, IF, WB, FACS, IP, ICC and functional assays
- • Varied antibody screening and purification technology
- • The five protein expression platforms for antigen and recombinant antibody preparation
- • Successfully screened dozens of candidate antibodies with high activity and druggability against several key targets
- • Established cell activity evaluation models for many antibodies against key drug targets (PD-1, PD-L1, and EGFR, etc)
- • A full set of preclinical research experience for multiple drug targets