|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|Human NAMPT Gene cDNA Clone (full-length ORF Clone), expression ready, N-GFPSpark-tagged||HG10990-ANG|
|Human NAMPT Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-tagged||HG10990-CF|
|Human NAMPT Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged||HG10990-M-F|
|Human NAMPT Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-tagged||HG10990-NF|
|Human NAMPT Gene cDNA Clone (full-length ORF Clone), expression ready, untagged||HG10990-UT|
|Learn more about expression Vectors|
Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferases. This enzyme participates in nicotinate and nicotinamide metabolism. This enzyme catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1- pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. NAMPT is also considered as an essential enzyme mediating granulocyte colony-stimulating factor (G-CSF)-triggered granulopoiesis in healthy individuals and in individuals with severe congenital neutropenia. Intracellular NAMPT and NAD+ amounts in myeloid cells, as well as plasma NAMPT and NAD+ levels, were increased by G-CSF treatment of both healthy volunteers and individuals with congenital neutropenia.