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Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone)

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KNG1/BDKcDNA Clone Product Information
Gene_bank_ref_id:NM_001102416.2
cDNA Size:1935
cDNA Description:ORF Clone of Homo sapiens kininogen 1, transcript variant 1 DNA.
Gene Synonym:BDK, KNG
Species:Human
Vector:pMD18-T Simple Vector
Restriction Site:
Tag Sequence:
Sequence Description:Identical with the Gene Bank Ref. ID sequence.
Shipping_carrier:Each tube contains approximately 10 μg of lyophilized plasmid.
Storage:The lyophilized plasmid can be stored at ambient temperature for three months.
pMD18-T Simple Vector Information

pMD18-T Simple Vector is a high-efficiency TA cloning vector constructed from pUC18, of which the initial multiple cloning sites (MCS) were destroyed. Thus the cDNA should be amplified by PCR with primers containing a restriction site for subclone. Competent cells appropriate for pUC18 are also appropriated for the Vector, e.g. JM109, DH5α, TOP10. The pMD18-T Simple Vector is 2.6kb in size. Selection of the plasmid in E. coli is conferred by the ampicillin resistance gene. The coding sequence was inserted by TA cloning at site 425.

pMD18-T Simple Usage Suggestion

The coding sequence can be amplified by PCR with M13-47 and RV-M primers.

Vector Sequence Download
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone) on other vectors
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, C-GFPSpark-taggedHG10529-ACG$345
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, C-OFPSpark tagHG10529-ACR$345
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-taggedHG10529-CF$315
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-taggedHG10529-CH$315
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-taggedHG10529-CM$315
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-taggedHG10529-CY$315
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-taggedHG10529-M-F$315
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone) expression ready, untaggedHG10529-M-N$315
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-taggedHG10529-NF$315
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-taggedHG10529-NH$315
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-taggedHG10529-NM$315
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-taggedHG10529-NY$315
Human KNG1 / BDK transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedHG10529-UT$315
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Background

Mouse kininogen-1, also known as high molecular weight kininogen, williams-Fitzgerald-Flaujeac factor, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, KNG1 and BDK, is a secreted protein which contains three cystatin domains. Kininogen-1 / KNG1 is a protein from the blood coagulation system as well as the kinin-kallikrein system. It is a protein that adsorbs to the surface of biomaterials that come in contact with blood. Kininogen-1 / KNG1 circulates throughout the blood and quickly adsorbs to the material surfaces. Kininogen-1 / KNG1 is one of the early participants of the intrinsic pathway of coagulation, together with Factor XII (Hageman factor) and prekallikrein. Kininogen-1 / KNG1 is one of the kininogens, a class of proteins. As with many other coagulation proteins, the protein was initially named after the patients in whom deficiency was first observed. When the clinical data were combined, it turned out that all patients, in fact, had a deficiency of the same protein. Defects in KNG1 are the cause of high molecular weight kininogen deficiency (HMWK deficiency) which is an autosomal recessive coagulation defect. Patients with HWMK deficiency do not have a hemorrhagic tendency, but they exhibit abnormal surface-mediated activation of fibrinolysis.

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Catalog:HG10529-M
List Price: $115.00  (Save $0.00)
Price:$115.00      [How to order]
Availability5 business days
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