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Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone)

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RSK4cDNA Clone Product Information
Gene_bank_ref_id:NM_014496.2
cDNA Size:2238
cDNA Description:ORF Clone of Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 6 (RPS6KA6) DNA.
Gene Synonym:RPS6KA6, RSK4
Species:Human
Vector:pMD18-T Simple Vector
Restriction Site:
Tag Sequence:
Sequence Description:Identical with the Gene Bank Ref. ID sequence.
Shipping_carrier:Each tube contains approximately 10 μg of lyophilized plasmid.
Storage:The lyophilized plasmid can be stored at ambient temperature for three months.
pMD18-T Simple Vector Information

pMD18-T Simple Vector is a high-efficiency TA cloning vector constructed from pUC18, of which the initial multiple cloning sites (MCS) were destroyed. Thus the cDNA should be amplified by PCR with primers containing a restriction site for subclone. Competent cells appropriate for pUC18 are also appropriated for the Vector, e.g. JM109, DH5α, TOP10. The pMD18-T Simple Vector is 2.6kb in size. Selection of the plasmid in E. coli is conferred by the ampicillin resistance gene. The coding sequence was inserted by TA cloning at site 425.

pMD18-T Simple Usage Suggestion

The coding sequence can be amplified by PCR with M13-47 and RV-M primers.

Vector Sequence Download
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone) on other vectors
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, C-GFPSpark-taggedHG10147-ACG$345
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, C-OFPSpark tagHG10147-ACR$345
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, N-GFPSpark-taggedHG10147-ANG$345
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, N-OFPSpark tagHG10147-ANR$345
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-taggedHG10147-CF$315
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-taggedHG10147-CH$315
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-taggedHG10147-CM$315
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-taggedHG10147-CY$315
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone) expression ready, FLAG-taggedHG10147-M-F$345
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, N-FLAG-taggedHG10147-NF$315
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-taggedHG10147-NH$315
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-taggedHG10147-NM$315
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-taggedHG10147-NY$315
Human RPS6KA6 / RSK4 Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedHG10147-UT$315
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Background

Ribosomal protein S6 kinase alpha-6, also known as Ribosomal S6 kinase 4, 90 kDa ribosomal protein S6 kinase 6,RSK-4, RSK4 and RPS6KA6, is a protein which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and S6 kinase subfamily. RPS6KA6 contains one AGC-kinase C-terminal domain and two protein kinase domains. RPS6KA6 forms a complex with either ERK1 or ERK2 in quiescent cells. RPS6KA6 shows a high level of homology to three isolated members of the human RSK family. RSK2 is involved in Coffin-Lowry syndrome and nonspecific MRX. The localization of RPS6KA6 in the interval that is commonly deleted in mentally retarded males together with the high degree of amino acid identity with RSK2 suggests that RPS6KA6 plays a role in normal neuronal development. Further mutation analyses in males with X-linked mental retardation must prove that the gene of RPS6KA6 is indeed a novel MRX gene. RPS6KA6 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. RPS6KA6 is activated by multiple phosphorylations on threonine and serine residues.

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Catalog:HG10147-M
List Price: $115.00  (Save $0.00)
Price:$115.00      [How to order]
Availability5 business days
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