|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human TXN2 ORF mammalian expression plasmid, C-GFPSpark tag||HG12557-ACG|
|Human TXN2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG12557-ACR|
|Human TXN2 ORF mammalian expression plasmid, N-GFPSpark tag||HG12557-ANG|
|Human TXN2 ORF mammalian expression plasmid, N-OFPSpark / RFP tag||HG12557-ANR|
|Human TXN2 ORF mammalian expression plasmid, C-Flag tag||HG12557-CF|
|Human TXN2 ORF mammalian expression plasmid, C-His tag||HG12557-CH|
|Human TXN2 ORF mammalian expression plasmid, C-Myc tag||HG12557-CM|
|Human TXN2 ORF mammalian expression plasmid, C-HA tag||HG12557-CY|
|Human TXN2 Gene cDNA clone plasmid||HG12557-G|
|Human TXN2 ORF mammalian expression plasmid, N-Flag tag||HG12557-NF|
|Human TXN2 ORF mammalian expression plasmid, N-His tag||HG12557-NH|
|Human TXN2 ORF mammalian expression plasmid, N-Myc tag||HG12557-NM|
|Human TXN2 ORF mammalian expression plasmid, N-HA tag||HG12557-NY|
|Human TXN2 natural ORF mammalian expression plasmid||HG12557-UT|
|Learn more about expression Vectors|
Thioredoxin-2, also known as TXN2, MTRX and TRX2, is a member of the thioredoxin family. Tryparedoxins (TXN) are thioredoxin-related proteins which, as trypanothione:peroxiredoxin oxidoreductases, constitute the trypanothione-dependent antioxidant defense and may also serve as substrates for ribonucleotide reductase in trypanosomatids. Thioredoxin-2 / TXN2 contains one thioredoxin domain. It is widely expressed in adult (at protein level) and fetal tissues. Human Thioredoxin-2 / TXN2 is a small redox protein important in cellular antioxidant defenses, as well as in the regulation of apoptosis. Thioredoxin-2 / TXN2 has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Thioredoxin-2 / TXN2 could be involved in the resistance to anti-tumor agents. It possesses a dithiol-reducing activity. Thioredoxin-2 / TXN2 plays an important role in protecting the mitochondria against oxidative stress and in sensitizing the cells to ROS-induced apoptosis. Mammalian Thioredoxin-2 / TXN2 is a mitochondrial isoform of highly evolutionary conserved thioredoxins. Thioredoxins are small ubiquitous protein-disulfide oxidoreductases implicated in a large variety of biological functions.