|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.
The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.
|Mouse LGALS7 ORF mammalian expression plasmid, C-GFPSpark tag||MG50404-ACG|
|Mouse LGALS7 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50404-ACR|
|Mouse LGALS7 ORF mammalian expression plasmid, C-Flag tag||MG50404-CF|
|Mouse LGALS7 ORF mammalian expression plasmid, C-His tag||MG50404-CH|
|Mouse LGALS7 ORF mammalian expression plasmid, C-Myc tag||MG50404-CM|
|Mouse LGALS7 ORF mammalian expression plasmid, C-HA tag||MG50404-CY|
|Mouse LGALS7 Gene cDNA clone plasmid||MG50404-M|
|Mouse LGALS7 ORF mammalian expression plasmid, N-Flag tag||MG50404-NF|
|Mouse LGALS7 ORF mammalian expression plasmid, N-His tag||MG50404-NH|
|Mouse LGALS7 ORF mammalian expression plasmid, N-Myc tag||MG50404-NM|
|Mouse LGALS7 ORF mammalian expression plasmid, N-HA tag||MG50404-NY|
|Mouse LGALS7 natural ORF mammalian expression plasmid||MG50404-UT|
|Learn more about expression Vectors|
LGALS7, also known as Galectin-7, is a member of the galectins family. The galectins are a family of beta-galactoside-binding proteins. There are at least 14 identified members in this family. Galectins share similarities in the CRD (the carbohydrate recognition domain). They are synthesized as cytosolic proteins. Though localized principally in the cytoplasm and lacking a classical signal peptide, galectins can also be stimulated to secretion by non-classical pathways or alternatively targeted to the nucleus. Galectins are implicated in modulating cell-cell and cell-matrix interactions. LGALS7 contains 1 galectin domain and is mainly expressed in stratified squamous epithelium. Galectin-7 could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. LGALS7 is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.