|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human VNN2 ORF mammalian expression plasmid, C-GFPSpark tag||HG11728-ACG|
|Human VNN2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11728-ACR|
|Human VNN2 ORF mammalian expression plasmid, C-Flag tag||HG11728-CF|
|Human VNN2 ORF mammalian expression plasmid, C-His tag||HG11728-CH|
|Human VNN2 ORF mammalian expression plasmid, C-Myc tag||HG11728-CM|
|Human VNN2 ORF mammalian expression plasmid, C-HA tag||HG11728-CY|
|Human VNN2 Gene cDNA clone plasmid||HG11728-G|
|Human VNN2 ORF mammalian expression plasmid, Flag tag||HG11728-G-F|
|Human VNN2 ORF mammalian expression plasmid, N-Flag tag||HG11728-NF|
|Human VNN2 ORF mammalian expression plasmid, N-His tag||HG11728-NH|
|Human VNN2 ORF mammalian expression plasmid, N-Myc tag||HG11728-NM|
|Human VNN2 ORF mammalian expression plasmid, N-HA tag||HG11728-NY|
|Human VNN2 natural ORF mammalian expression plasmid||HG11728-UT|
|Learn more about expression Vectors|
Vascular non-inflammatory molecule 2, also known as glycosyl-phosphatidyl inositol-anchored protein GPI-80, Vanin-2, Protein FOAP-4 and VNN2, is a cell membrane protein which belongs to the CN hydrolase family and Vanin subfamily. VNN2 is widely expressed with higher expression in spleen and blood. VNN2 is a member of the vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. VNN2 is an amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. It is involved in the thymus homing of bone marrow cells. VNN2 plays a role in transendothelial migration of neutrophils and may regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil.