|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human FAM3D ORF mammalian expression plasmid, C-GFPSpark tag||HG11659-ACG|
|Human FAM3D ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11659-ACR|
|Human FAM3D ORF mammalian expression plasmid, C-Flag tag||HG11659-CF|
|Human FAM3D ORF mammalian expression plasmid, C-His tag||HG11659-CH|
|Human FAM3D ORF mammalian expression plasmid, C-Myc tag||HG11659-CM|
|Human FAM3D ORF mammalian expression plasmid, C-HA tag||HG11659-CY|
|Human FAM3D Gene cDNA clone plasmid||HG11659-M|
|Human FAM3D ORF mammalian expression plasmid, N-Flag tag||HG11659-NF|
|Human FAM3D ORF mammalian expression plasmid, N-His tag||HG11659-NH|
|Human FAM3D ORF mammalian expression plasmid, N-Myc tag||HG11659-NM|
|Human FAM3D ORF mammalian expression plasmid, N-HA tag||HG11659-NY|
|Human FAM3D natural ORF mammalian expression plasmid||HG11659-UT|
|Learn more about expression Vectors|
Family with sequence similarity 3 (FAM3) family is a novel cytokine-like gene family, which has four genes in this family, FAM3A, FAM3B, FAM3C, and FAM3D, each encoding a protein (224-235 amino acids) with a hydrophobic leader sequence. It had indicated that FAM3B/PANDER (pancreatic derived factor) is highly expressed in pancreas, and FAM3A and FAM3C in almost all tissues. FAM3D is abundantly expressed in placenta and weakly expressed in small intestine. Immunohistochemistry showed that FAM3A is expressed prominently in the vascular endothelium, particularly capillaries. FAM3A and FAM3B protein were both localized to the islets of Langerhans of the endocrine pancreas. Recombinant FAM3B protein has delayed effects on beta-cell function. FAM3C is involved in retinal laminar formation processes in vertebrates. NFATC2, SCP2, CACNA1C, TCRA, POLE, and FAM3D, were associated with narcolepsy. Some of these associations were further supported by gene expression analyses and an association study in essential hypersomnia (EHS), CNS hypersonia similar to narcolepsy.