|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human REG1B ORF mammalian expression plasmid, C-GFPSpark tag||HG11638-ACG|
|Human REG1B ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11638-ACR|
|Human REG1B ORF mammalian expression plasmid, C-Flag tag||HG11638-CF|
|Human REG1B ORF mammalian expression plasmid, C-His tag||HG11638-CH|
|Human REG1B ORF mammalian expression plasmid, C-Myc tag||HG11638-CM|
|Human REG1B ORF mammalian expression plasmid, C-HA tag||HG11638-CY|
|Human REG1B Gene cDNA clone plasmid||HG11638-M|
|Human REG1B ORF mammalian expression plasmid, N-Flag tag||HG11638-NF|
|Human REG1B ORF mammalian expression plasmid, N-His tag||HG11638-NH|
|Human REG1B ORF mammalian expression plasmid, N-Myc tag||HG11638-NM|
|Human REG1B ORF mammalian expression plasmid, N-HA tag||HG11638-NY|
|Human REG1B natural ORF mammalian expression plasmid||HG11638-UT|
|Learn more about expression Vectors|
Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells, and could be associated with fibrocalculous pancreatopathy. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family consisting of four subtypes (types I, II, III, IV) and are involved in cancers and neurodegenerative diseases. Regenerating islet-derived 1 beta (REG1B), also known as Lithostathine-1-beta and Pancreatic stone protein 2 (PSPS2), is a types I Reg protein and contains one typical C-type lectin domain. REG1B is a 166-amino acid protein which has 22 amino acid substitutions in comparison with the previously isolated human REG1A, and it is was expressed only in pancreas. REG1B Is normally found in the exocrine pancreas, whereas in other tissues it appears either only under pathological conditions, such as Alzheimer's disease (brain), cancer (colon), or during regeneration such as neuronal sprouting in brain and pancreas regeneration. REG1B might act as an inhibitor of spontaneous calcium carbonate precipitation. The REG1A and REG1B gene and proteins could play different roles in the pancreas.