|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human MGAT5 ORF mammalian expression plasmid, C-GFPSpark tag||HG11373-ACG|
|Human MGAT5 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11373-ACR|
|Human MGAT5 ORF mammalian expression plasmid, C-Flag tag||HG11373-CF|
|Human MGAT5 ORF mammalian expression plasmid, C-His tag||HG11373-CH|
|Human MGAT5 ORF mammalian expression plasmid, C-Myc tag||HG11373-CM|
|Human MGAT5 ORF mammalian expression plasmid, C-HA tag||HG11373-CY|
|Human MGAT5 Gene cDNA clone plasmid||HG11373-M|
|Human MGAT5 ORF mammalian expression plasmid, N-Flag tag||HG11373-NF|
|Human MGAT5 ORF mammalian expression plasmid, N-His tag||HG11373-NH|
|Human MGAT5 ORF mammalian expression plasmid, N-Myc tag||HG11373-NM|
|Human MGAT5 ORF mammalian expression plasmid, N-HA tag||HG11373-NY|
|Human MGAT5 natural ORF mammalian expression plasmid||HG11373-UT|
|Learn more about expression Vectors|
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, also known as Alpha-mannoside beta-1,6-N-acetylglucosaminyl-transferase, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferase V, MGAT5 and GGNT5, is a single-pass type I I membrane protein which belongs to the glycosyltransferase 18 family. MGAT5 / GGNT5 catalyzes the addition of N-acetylglucosamine in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. The central nervous system (CNS) is rich in glycoconjugates, located on cell surface and in extracellular matrix. MGAT5 / GGNT5 modification of complex-type N-glycans on CNS glycoproteins is involved in the regulation of depression-like behavior. Inhibitors of MGAT5 / GGNT5 might be useful in the treatment of malignancies by targeting their dependency on focal adhesion signaling for growth and metastasis.