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Rhesus ADAM8 Protein (His Tag)

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 CD156/ADAM8 Protein Product Information
Synonym:ADAM8
Protein Construction:A DNA sequence encoding the rhesus ADAM8 (XP_002805919.1) (Met1-Pro497) was expressed with a polyhistidine tag at the C-terminus.
Species:Rhesus
Expressed Host:Human Cells
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
 CD156/ADAM8 Protein QC Testing
Purity:(50.8+34.6) % as determined by SDS-PAGE
Bio-Activity:Measured by its ability to cleave a fluorogenic peptide substrate Mca-PLAQAV-Dpa-RSSSR-NH2, R&D Systems, Catalog # ES003.
The specific activity is > 0.5 pmols/min/μg.
Endotoxin:< 1.0 EU per μg of the protein as determined by the LAL method
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Arg 21
Molecule Mass:The recombinant rhesus ADAM8 comprises 488 amino acids and has a calculated molecular mass of 53.6 KDa.
Formulation:Lyophilized from sterile 12.5mM Tris, 5mM CaCl2, 75mM NaCl, 50% glycerol.
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
 CD156/ADAM8 Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
 CD156/ADAM8 Protein SDS-PAGE
Cynomolgus ADAM8 Protein (His Tag) SDS-PAGE
Other CD156/ADAM8 Recombinant Protein Products
90278-C08H
ADAM8(CD156) Background

ADAM8, also known as CD156, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM8 is possiblely involved in extravasation of leukocytes As a metalloprotease, ADAM8 also may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma.

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Catalog: 90278-C08H-10
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"