|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human RCN3 ORF mammalian expression plasmid, C-GFPSpark tag||HG13533-ACG|
|Human RCN3 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG13533-ACR|
|Human RCN3 ORF mammalian expression plasmid, C-Flag tag||HG13533-CF|
|Human RCN3 ORF mammalian expression plasmid, C-His tag||HG13533-CH|
|Human RCN3 ORF mammalian expression plasmid, C-Myc tag||HG13533-CM|
|Human RCN3 ORF mammalian expression plasmid, C-HA tag||HG13533-CY|
|Human RCN3 Gene cDNA clone plasmid||HG13533-G|
|Human RCN3 ORF mammalian expression plasmid, N-Flag tag||HG13533-NF|
|Human RCN3 ORF mammalian expression plasmid, N-His tag||HG13533-NH|
|Human RCN3 ORF mammalian expression plasmid, N-Myc tag||HG13533-NM|
|Human RCN3 ORF mammalian expression plasmid, N-HA tag||HG13533-NY|
|Human RCN3 natural ORF mammalian expression plasmid||HG13533-UT|
|Learn more about expression Vectors|
RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents the target sequence of subtilisin-like proprotein convertases(SPCs). SPCs are a family of seven structurally related serine endoproteases that are involved in the proteolytic activation of proproteins.RCN3 is transiently associated with proPACE4, but not with mature PACE4. Inhibition of PACE4 maturation by a Ca2+ ionophore resulted in accumulation of the proPACE4-RCN-3 complex in cells. It has been proposed that elective and transient association of RCN3 with the precursor of PACE4 plays an important role in the biosynthesis of PACE4.