|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human NTMT1 ORF mammalian expression plasmid, C-GFPSpark tag||HG11222-ACG|
|Human NTMT1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11222-ACR|
|Human NTMT1 ORF mammalian expression plasmid, N-GFPSpark tag||HG11222-ANG|
|Human NTMT1 ORF mammalian expression plasmid, N-OFPSpark / RFP tag||HG11222-ANR|
|Human NTMT1 ORF mammalian expression plasmid, C-Flag tag||HG11222-CF|
|Human NTMT1 ORF mammalian expression plasmid, C-His tag||HG11222-CH|
|Human NTMT1 ORF mammalian expression plasmid, C-Myc tag||HG11222-CM|
|Human NTMT1 ORF mammalian expression plasmid, C-HA tag||HG11222-CY|
|Human NTMT1 Gene cDNA clone plasmid||HG11222-M|
|Human NTMT1 ORF mammalian expression plasmid, N-Flag tag||HG11222-NF|
|Human NTMT1 ORF mammalian expression plasmid, N-His tag||HG11222-NH|
|Human NTMT1 ORF mammalian expression plasmid, N-Myc tag||HG11222-NM|
|Human NTMT1 ORF mammalian expression plasmid, N-HA tag||HG11222-NY|
|Human NTMT1 natural ORF mammalian expression plasmid||HG11222-UT|
|Learn more about expression Vectors|
Methyltransferase-like protein 11A, also known as METTL11A, is a member of the methyltransferase superfamily and METTL11 family. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Methylation often occurs on nucleic bases in DNA or amino acids in protein structures. Methytransferase uses a reactive methyl group bound to sulfur in S-adenosyl methionine (SAM) as the methyl donor. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. This methylation occurs on cytosine residues. DNA methylation may be necessary for normal growth from embryonic stages in mammals. Methylation can serve to protect DNA from enzymatic cleavage, since restriction enzymes are unable to bind and recognize externally modified sequences. This is especially useful in bacterial restriction modification systems which use restriction enzymes to cleave foreign DNA while keeping their own DNA protected by methylation. Methylation of amino acids in the formation of proteins leads to more diversity of possible amino acids and therefore more diversity of function. The methylation reaction occurs on nitrogen atoms either on the N terminus or side-chain position of the protein and are usually irreversible.