|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human JTB ORF mammalian expression plasmid, C-GFPSpark tag||HG13447-ACG|
|Human JTB ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG13447-ACR|
|Human JTB ORF mammalian expression plasmid, C-Flag tag||HG13447-CF|
|Human JTB ORF mammalian expression plasmid, C-His tag||HG13447-CH|
|Human JTB ORF mammalian expression plasmid, C-Myc tag||HG13447-CM|
|Human JTB ORF mammalian expression plasmid, C-HA tag||HG13447-CY|
|Human JTB Gene cDNA clone plasmid||HG13447-G|
|Human JTB ORF mammalian expression plasmid, N-Flag tag||HG13447-NF|
|Human JTB ORF mammalian expression plasmid, N-His tag||HG13447-NH|
|Human JTB ORF mammalian expression plasmid, N-Myc tag||HG13447-NM|
|Human JTB ORF mammalian expression plasmid, N-HA tag||HG13447-NY|
|Human JTB natural ORF mammalian expression plasmid||HG13447-UT|
|Learn more about expression Vectors|
Jumping translocation breakpoint, also known as JTB, is a member of the JTB family. Jumping translocation (JT) is an unbalanced translocation that comprises amplified chromosomalsegments jumping to various telomeres. JTB is expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts. It is required for normal cytokinesis during mitosis. JTB plays a role in the regulation of cell proliferation. It may be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.