|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human TFRC ORF mammalian expression plasmid, C-GFPSpark tag||HG11020-ACG|
|Human TFRC ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11020-ACR|
|Human TFRC ORF mammalian expression plasmid, C-Flag tag||HG11020-CF|
|Human TFRC ORF mammalian expression plasmid, C-His tag||HG11020-CH|
|Human TFRC ORF mammalian expression plasmid, C-Myc tag||HG11020-CM|
|Human TFRC ORF mammalian expression plasmid, C-HA tag||HG11020-CY|
|Human TFRC Gene cDNA clone plasmid||HG11020-M|
|Human TFRC ORF mammalian expression plasmid, N-Flag tag||HG11020-NF|
|Human TFRC ORF mammalian expression plasmid, N-His tag||HG11020-NH|
|Human TFRC ORF mammalian expression plasmid, N-Myc tag||HG11020-NM|
|Human TFRC ORF mammalian expression plasmid, N-HA tag||HG11020-NY|
|Human TFRC natural ORF mammalian expression plasmid||HG11020-UT|
|Learn more about expression Vectors|
Mouse transferrin receptor protein 1, also known as transferrin receptor, Trfr, p90, CD71 and TFRC, is a single-pass type II membrane protein which belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.