|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human CALCB ORF mammalian expression plasmid, C-GFPSpark tag||HG13283-ACG|
|Human CALCB ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG13283-ACR|
|Human CALCB ORF mammalian expression plasmid, C-Flag tag||HG13283-CF|
|Human CALCB ORF mammalian expression plasmid, C-His tag||HG13283-CH|
|Human CALCB ORF mammalian expression plasmid, C-Myc tag||HG13283-CM|
|Human CALCB ORF mammalian expression plasmid, C-HA tag||HG13283-CY|
|Human CALCB Gene cDNA clone plasmid||HG13283-G|
|Human CALCB ORF mammalian expression plasmid, N-Flag tag||HG13283-NF|
|Human CALCB ORF mammalian expression plasmid, N-His tag||HG13283-NH|
|Human CALCB ORF mammalian expression plasmid, N-Myc tag||HG13283-NM|
|Human CALCB ORF mammalian expression plasmid, N-HA tag||HG13283-NY|
|Human CALCB natural ORF mammalian expression plasmid||HG13283-UT|
|Learn more about expression Vectors|
CALCB, also known as CGPR and calcitonin 2, belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin, blood, and cerebrospinal fluid. CGRP immunolabeling (IL) was detected in epidermal keratinocytes at levels that were especially high and widespread in the skin of humans from locations afflicted with postherpetic neuralgia (PHN) and complex region pain syndrome type 1 (CRPS), of monkeys infected with simian immunodeficiency virus, and of rats subjected to L5/L6 spinal nerve ligation, sciatic nerve chronic constriction, and subcutaneous injection of complete Freund's adjuvant. Increased CGRP-IL was also detected in epidermal keratinocytes of transgenic mice with keratin-14 promoter driven overexpression of noggin, an antagonist to BMP-4 signaling. CGPR dilates a variety of vessels including the coronary, cerebral and systemic vasculature.