|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human SDF2 ORF mammalian expression plasmid, C-GFPSpark tag||HG10950-ACG|
|Human SDF2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10950-ACR|
|Human SDF2 ORF mammalian expression plasmid, C-Flag tag||HG10950-CF|
|Human SDF2 ORF mammalian expression plasmid, C-His tag||HG10950-CH|
|Human SDF2 ORF mammalian expression plasmid, C-Myc tag||HG10950-CM|
|Human SDF2 ORF mammalian expression plasmid, C-HA tag||HG10950-CY|
|Human SDF2 Gene cDNA clone plasmid||HG10950-M|
|Human SDF2 ORF mammalian expression plasmid, Flag tag||HG10950-M-F|
|Human SDF2 ORF mammalian expression plasmid, N-Flag tag||HG10950-NF|
|Human SDF2 ORF mammalian expression plasmid, N-His tag||HG10950-NH|
|Human SDF2 ORF mammalian expression plasmid, N-Myc tag||HG10950-NM|
|Human SDF2 ORF mammalian expression plasmid, N-HA tag||HG10950-NY|
|Human SDF2 natural ORF mammalian expression plasmid||HG10950-UT|
|Learn more about expression Vectors|
Stromal derived factors (SDFs) are a loosely defined group of molecules that are generated by stromal cells. Two of the stromal derived factors, SDF-1 and SDF-4 belong to the chemokine family. Other SDFs, such as SDF-2 and SDF-5 are not well defined and their biological functions are less known. SDF-2 is first isolated from the mouse stromal cell line ST2 as a secretory protein. The amino acid sequence deduced from the murine clone and the human homolog are conserved more than 92 %, and the aa sequence of SDF-2 shows similarity to those of yeast dolichyl phosphate-D-mannose, protein mannosyltransferases. SDF-1 and its receptor are strongly indicated in the progression of various cancers including breast cancer. SDF-2, SDF2-L1, SDF-4, and SDF-5 are ubiquitously expressed in various cancer cell lines and SDF-2, SDF-4 and SDF-5 are expressed in mammary tissues. These SDFs have prognostic value and warrant further investigation in their biological functions and clinical value.