|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human TYRP1 ORF mammalian expression plasmid, C-GFPSpark tag||HG13224-ACG|
|Human TYRP1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG13224-ACR|
|Human TYRP1 ORF mammalian expression plasmid, C-Flag tag||HG13224-CF|
|Human TYRP1 ORF mammalian expression plasmid, C-His tag||HG13224-CH|
|Human TYRP1 ORF mammalian expression plasmid, C-Myc tag||HG13224-CM|
|Human TYRP1 ORF mammalian expression plasmid, C-HA tag||HG13224-CY|
|Human TYRP1 Gene cDNA clone plasmid||HG13224-G|
|Human TYRP1 ORF mammalian expression plasmid, N-Flag tag||HG13224-NF|
|Human TYRP1 ORF mammalian expression plasmid, N-His tag||HG13224-NH|
|Human TYRP1 ORF mammalian expression plasmid, N-Myc tag||HG13224-NM|
|Human TYRP1 ORF mammalian expression plasmid, N-HA tag||HG13224-NY|
|Human TYRP1 natural ORF mammalian expression plasmid||HG13224-UT|
|Learn more about expression Vectors|
Tyrosinase-related protein 1, also known as TYRP1 or TRP1, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Mutations in this enzyme are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. TYRP1 / TRP1 is involved in the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. This enzyme may regulate or influence the type of melanin synthesized. The expression of Tyrosinase-related protein 1 (TYRP1) is regulated by the microphthalmia-associated transcription factor (MITF). There is mounting evidence demonstrating that in addition to its role in eumelanin synthesis, TYRP1 is involved in maintaining stability of tyrosinase proliferation and melanocyte cell death.