|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human PLA2G7 ORF mammalian expression plasmid, C-GFPSpark tag||HG10848-ACG|
|Human PLA2G7 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10848-ACR|
|Human PLA2G7 ORF mammalian expression plasmid, C-Flag tag||HG10848-CF|
|Human PLA2G7 ORF mammalian expression plasmid, C-His tag||HG10848-CH|
|Human PLA2G7 ORF mammalian expression plasmid, C-Myc tag||HG10848-CM|
|Human PLA2G7 ORF mammalian expression plasmid, C-HA tag||HG10848-CY|
|Human PLA2G7 Gene cDNA clone plasmid||HG10848-M|
|Human PLA2G7 ORF mammalian expression plasmid, N-Flag tag||HG10848-NF|
|Human PLA2G7 ORF mammalian expression plasmid, N-His tag||HG10848-NH|
|Human PLA2G7 ORF mammalian expression plasmid, N-Myc tag||HG10848-NM|
|Human PLA2G7 ORF mammalian expression plasmid, N-HA tag||HG10848-NY|
|Human PLA2G7 natural ORF mammalian expression plasmid||HG10848-UT|
|Learn more about expression Vectors|
Platelet-activating factor acetylhydrolase, also known as 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycero-phosphocholine esterase, Group-VIIA phospholipase A2, LDL-associated phospholipase A2, PAF 2-acylhydrolase, PLA2G7 and PAFAH, is secreted protein which belongs to the AB hydrolase superfamily and Lipase family. PLA2G7 / PAFAH modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. It has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids. PLA2G7 / PAFAH is a potent pro- and anti-inflammatory molecule that has been implicated in multiple inflammatory disease processes, including cardiovascular disease. PLA2G7 also represents an important, potentially functional candidate in the pathophysiology of coronary artery disease (CAD). Defects in PLA2G7 are the cause of platelet-activating factor acetylhydrolase deficiency (PLA2G7 deficiency). It is a trait which is present in 27% of Japanese. It could have a significant physiologic effect in the presence of inflammatory bodily responses.