|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human Acrp30 ORF mammalian expression plasmid, C-GFPSpark tag||HG10772-ACG|
|Human Acrp30 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10772-ACR|
|Human Acrp30 ORF mammalian expression plasmid, C-Flag tag||HG10772-CF|
|Human Acrp30 ORF mammalian expression plasmid, C-His tag||HG10772-CH|
|Human Acrp30 ORF mammalian expression plasmid, C-Myc tag||HG10772-CM|
|Human Acrp30 ORF mammalian expression plasmid, C-HA tag||HG10772-CY|
|Human Acrp30 Gene cDNA clone plasmid||HG10772-M|
|Human Acrp30 natural ORF mammalian expression plasmid||HG10772-M-N|
|Human Acrp30 ORF mammalian expression plasmid, N-Flag tag||HG10772-NF|
|Human Acrp30 ORF mammalian expression plasmid, N-His tag||HG10772-NH|
|Human Acrp30 ORF mammalian expression plasmid, N-Myc tag||HG10772-NM|
|Human Acrp30 ORF mammalian expression plasmid, N-HA tag||HG10772-NY|
|Human Acrp30 natural ORF mammalian expression plasmid||HG10772-UT|
|Learn more about expression Vectors|
Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other tissues. Adiponectin mediates its actions in the periphery mainly via two receptors, AdipoR1 and AdipoR2. Adiponectin influences gonadotropin release, normal pregnancy, and assisted reproduction outcomes. Adiponectin, a beneficial adipokine, represents a major link between obesity and reproduction. Higher levels of adiponectin are associated with improved menstrual function and better outcomes in assisted reproductive cycles. Unlike other adipocytokines produced by adipose tissue, adiponectin appears to have anti-inflammatory, anti-diabetic, and anti-atherogenic properties. Several clinical studies demonstrate the inverse relationship between plasma adiponectin levels and several inflammatory markers including C-reactive protein. Adiponectin attenuates inflammatory responses to multiple stimuli by modulating signaling pathways in a variety of cell types. The anti-inflammatory properties of adiponectin may be a major component of its beneficial effects on cardiovascular and metabolic disorders including atherosclerosis and insulin resistance. Additionally, it is important factor in chronic liver diseases and chronic kidney diseases. Some cancer cell types express adiponectin receptors. Thus Adiponectin may act on tumour cells directly by binding and activating adiponectin receptors and downstream signalling pathways.