|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human CD47 ORF mammalian expression plasmid, C-GFPSpark tag||HG12283-ACG|
|Human CD47 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG12283-ACR|
|Human CD47 ORF mammalian expression plasmid, C-Flag tag||HG12283-CF|
|Human CD47 ORF mammalian expression plasmid, C-His tag||HG12283-CH|
|Human CD47 ORF mammalian expression plasmid, C-Myc tag||HG12283-CM|
|Human CD47 ORF mammalian expression plasmid, C-HA tag||HG12283-CY|
|Human CD47 Gene cDNA clone plasmid||HG12283-G|
|Human CD47 natural ORF mammalian expression plasmid||HG12283-G-N|
|Human CD47 ORF mammalian expression plasmid, N-Flag tag||HG12283-NF|
|Human CD47 ORF mammalian expression plasmid, N-His tag||HG12283-NH|
|Human CD47 ORF mammalian expression plasmid, N-Myc tag||HG12283-NM|
|Human CD47 ORF mammalian expression plasmid, N-HA tag||HG12283-NY|
|Human CD47 natural ORF mammalian expression plasmid||HG12283-UT|
|Learn more about expression Vectors|
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.