|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human BTC ORF mammalian expression plasmid, C-GFPSpark tag||HG12192-ACG|
|Human BTC ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG12192-ACR|
|Human BTC ORF mammalian expression plasmid, C-Flag tag||HG12192-CF|
|Human BTC ORF mammalian expression plasmid, C-His tag||HG12192-CH|
|Human BTC ORF mammalian expression plasmid, C-Myc tag||HG12192-CM|
|Human BTC ORF mammalian expression plasmid, C-HA tag||HG12192-CY|
|Human BTC Gene cDNA clone plasmid||HG12192-G|
|Human BTC ORF mammalian expression plasmid, Flag tag||HG12192-G-F|
|Human BTC ORF mammalian expression plasmid, N-Flag tag||HG12192-NF|
|Human BTC ORF mammalian expression plasmid, N-His tag||HG12192-NH|
|Human BTC ORF mammalian expression plasmid, N-Myc tag||HG12192-NM|
|Human BTC ORF mammalian expression plasmid, N-HA tag||HG12192-NY|
|Human BTC natural ORF mammalian expression plasmid||HG12192-UT|
|Learn more about expression Vectors|
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinases encoded by the ErbB gene family (ErbB-1/epidermal growth factor receptor (EGFR), neu/ErbB-2/HER2, ErbB-3/HER3 and ErbB-4/HER4). Betacellulin is a 32-kilodalton glycoprotein that appears to be processed from a larger transmembrane precursor by proteolytic cleavage. This protein is a ligand for the EGF receptor. BTC is a polymer of about 62-111 amino acid residues. Secondary Structure: 6% helical (1 helices; 3 residues)36% beta sheet (5 strands; 18 residues). BTC was originally identified as a growth-promoting factor in mouse pancreatic β-cell carcinoma cell line and has since been identified in humans. It plays a role in the growth and development of the neonate and/or mammary gland function. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.