|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human EFNA4 ORF mammalian expression plasmid, C-GFPSpark tag||HG12087-ACG|
|Human EFNA4 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG12087-ACR|
|Human EFNA4 ORF mammalian expression plasmid, C-Flag tag||HG12087-CF|
|Human EFNA4 ORF mammalian expression plasmid, C-His tag||HG12087-CH|
|Human EFNA4 ORF mammalian expression plasmid, C-Myc tag||HG12087-CM|
|Human EFNA4 ORF mammalian expression plasmid, C-HA tag||HG12087-CY|
|Human EFNA4 Gene cDNA clone plasmid||HG12087-G|
|Human EFNA4 ORF mammalian expression plasmid, N-Flag tag||HG12087-NF|
|Human EFNA4 ORF mammalian expression plasmid, N-His tag||HG12087-NH|
|Human EFNA4 ORF mammalian expression plasmid, N-Myc tag||HG12087-NM|
|Human EFNA4 ORF mammalian expression plasmid, N-HA tag||HG12087-NY|
|Human EFNA4 natural ORF mammalian expression plasmid||HG12087-UT|
|Learn more about expression Vectors|
EPH-related receptor tyrosine kinase ligand 4 (Ephrin-A4) also known as EFNA4, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. Ephrin-A4/EFNA4 functions as a cell surface GPI-bound ligand for Eph receptor, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.