|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human LOXL2 ORF mammalian expression plasmid, C-GFPSpark tag||HG11664-ACG|
|Human LOXL2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11664-ACR|
|Human LOXL2 ORF mammalian expression plasmid, C-Flag tag||HG11664-CF|
|Human LOXL2 ORF mammalian expression plasmid, C-His tag||HG11664-CH|
|Human LOXL2 ORF mammalian expression plasmid, C-Myc tag||HG11664-CM|
|Human LOXL2 ORF mammalian expression plasmid, C-HA tag||HG11664-CY|
|Human LOXL2 Gene cDNA clone plasmid||HG11664-M|
|Human LOXL2 ORF mammalian expression plasmid, N-Flag tag||HG11664-NF|
|Human LOXL2 ORF mammalian expression plasmid, N-His tag||HG11664-NH|
|Human LOXL2 ORF mammalian expression plasmid, N-Myc tag||HG11664-NM|
|Human LOXL2 ORF mammalian expression plasmid, N-HA tag||HG11664-NY|
|Human LOXL2 natural ORF mammalian expression plasmid||HG11664-UT|
|Learn more about expression Vectors|
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein which belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme activity; and more divergent propeptide regions. LOX family enzyme activities catalyze the final enzymatic conversion required for the formation of normal biosynthetic collagen and elastin cross-links. LOXL2 is expressed by pre-hypertrophic and hypertrophic chondrocytes in vivo, and that LOXL2 expression is regulated in vitro as a function of chondrocyte differentiation. LOXL2 promotes chondrocyte differentiation by mechanisms that are likely to include roles as both a regulator and an effector of chondrocyte differentiation. LOXL2 expression could also be explored as a molecular target in the prevention of breast cancer progression.