|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human VNN1 ORF mammalian expression plasmid, C-GFPSpark tag||HG11662-ACG|
|Human VNN1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11662-ACR|
|Human VNN1 ORF mammalian expression plasmid, C-Flag tag||HG11662-CF|
|Human VNN1 ORF mammalian expression plasmid, C-His tag||HG11662-CH|
|Human VNN1 ORF mammalian expression plasmid, C-Myc tag||HG11662-CM|
|Human VNN1 ORF mammalian expression plasmid, C-HA tag||HG11662-CY|
|Human VNN1 Gene cDNA clone plasmid||HG11662-M|
|Human VNN1 ORF mammalian expression plasmid, N-Flag tag||HG11662-NF|
|Human VNN1 ORF mammalian expression plasmid, N-His tag||HG11662-NH|
|Human VNN1 ORF mammalian expression plasmid, N-Myc tag||HG11662-NM|
|Human VNN1 ORF mammalian expression plasmid, N-HA tag||HG11662-NY|
|Human VNN1 natural ORF mammalian expression plasmid||HG11662-UT|
|Learn more about expression Vectors|
Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one CN hydrolase domain. It is widely expressed with higher expression in spleen, kidney and blood. It is overexpressed in lesional psoriatic skin. Vanin-1 is also a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. Vanin-1 is an epithelial pantetheinase that provides cysteamine to tissue and regulates response to stress. Vanin-1 is expressed by enterocytes, and its absence limits intestinal epithelial cell production of proinflammatory signals. Vanin-1 regulates late adhesion steps of thymus homing under physiological, noninflammatory conditions. The early impact of vanin-1 deficiency on tumor induction was directly correlated to the amount of inflammation and subsequent epithelial proliferation rather than cell death rate. Vanin-1 molecule was shown to be involved in the control of thymus reconstitution following sublethal irradiation.