|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human NLGN1 ORF mammalian expression plasmid, C-GFPSpark tag||HG11617-ACG|
|Human NLGN1 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11617-ACR|
|Human NLGN1 ORF mammalian expression plasmid, C-Flag tag||HG11617-CF|
|Human NLGN1 ORF mammalian expression plasmid, C-His tag||HG11617-CH|
|Human NLGN1 ORF mammalian expression plasmid, C-Myc tag||HG11617-CM|
|Human NLGN1 ORF mammalian expression plasmid, C-HA tag||HG11617-CY|
|Human NLGN1 Gene cDNA clone plasmid||HG11617-M|
|Human NLGN1 ORF mammalian expression plasmid, Myc tag||HG11617-M-M|
|Human NLGN1 ORF mammalian expression plasmid, N-Flag tag||HG11617-NF|
|Human NLGN1 ORF mammalian expression plasmid, N-His tag||HG11617-NH|
|Human NLGN1 ORF mammalian expression plasmid, N-Myc tag||HG11617-NM|
|Human NLGN1 ORF mammalian expression plasmid, N-HA tag||HG11617-NY|
|Human NLGN1 natural ORF mammalian expression plasmid||HG11617-UT|
|Learn more about expression Vectors|
Neuroligin 1 (NLGN1) belongs to the type-B carboxylesterase/lipase family, is a synaptic cell-adhesion molecule that is enriched in postsynaptic densities where it may recruit receptors, channels, and signal-transduction molecules to synaptic sites of cell adhesion. Neuroligins consist of five members (NLGN1, NLGN2, NLGN3, NLGN4 and NLGN4Y), which interact with beta-neurexins and this interaction is involved in the formation of functional synapses. The extracellular domain of functional Neuroligin 1 associates as a dimer when analyzed by sedimentation equilibrium. Neuroligin 1 has a unique N-linked glycosylation pattern in the neuroligin family, and glycosylation and its processing modify neuroligin activity. Neuroligin 1 is a potent trigger for the de novo formation of synaptic connections, and it has recently been suggested that it is required for the maturation of functionally competent excitatory synapses. The persistent expression of Neuroligin 1 is required for the maintenance of NMDAR-mediated synaptic transmission, which enables normal development of synaptic plasticity and long-term memory in the amygdala of adult animals.