|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.
Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokaryotic expression systems.
|Human SCG2 ORF mammalian expression plasmid, C-GFPSpark tag||HG13441-ACG|
|Human SCG2 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG13441-ACR|
|Human SCG2 ORF mammalian expression plasmid, C-Flag tag||HG13441-CF|
|Human SCG2 ORF mammalian expression plasmid, C-His tag||HG13441-CH|
|Human SCG2 ORF mammalian expression plasmid, C-Myc tag||HG13441-CM|
|Human SCG2 ORF mammalian expression plasmid, C-HA tag||HG13441-CY|
|Human SCG2 Gene cDNA clone plasmid||HG13441-G|
|Human SCG2 ORF mammalian expression plasmid, N-Flag tag||HG13441-NF|
|Human SCG2 ORF mammalian expression plasmid, N-His tag||HG13441-NH|
|Human SCG2 ORF mammalian expression plasmid, N-Myc tag||HG13441-NM|
|Human SCG2 ORF mammalian expression plasmid, N-HA tag||HG13441-NY|
|Human SCG2 natural ORF mammalian expression plasmid||HG13441-UT|
|Learn more about expression Vectors|
Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein which belongs to the SCF family. KITL / kit ligand also belongs to the family of dimeric transmembrane growth factors. The soluble form of KIT ligand is a secreted protein. Mast cells are thought to participate in a variety of immune responses, such as parasite resistance and the allergic reaction. Mast cell development depends on stem cell factor (Kit ligand) and its receptor, c-Kit. KITL / kit ligand stimulates the proliferation of mast cells. KITL / kit ligand is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Efficient cell surface presentation of KITL / kit ligand is essential for the migration, proliferation, and survival of melanocytes, germ cells, hemopoietic stem cells, and mastocytes. KITL / kit ligand acts synergistically with other cytokines, probably interleukins. KITL / kit ligand plays a crucial role in the development and maintenance of the melanocyte lineage in adult skin. It exerts permanent survival, proliferation and migration functions in Kit receptor-expressing melanocytes. KITL / kit ligand misexpression in some hyperpigmented lesions may open the avenue for Kitl-dependent treatment of pathological skin conditions.