|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human ENPP5 ORF mammalian expression plasmid, C-GFPSpark tag||HG11519-ACG|
|Human ENPP5 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11519-ACR|
|Human ENPP5 ORF mammalian expression plasmid, C-Flag tag||HG11519-CF|
|Human ENPP5 ORF mammalian expression plasmid, C-His tag||HG11519-CH|
|Human ENPP5 ORF mammalian expression plasmid, C-Myc tag||HG11519-CM|
|Human ENPP5 ORF mammalian expression plasmid, C-HA tag||HG11519-CY|
|Human ENPP5 Gene cDNA clone plasmid||HG11519-M|
|Human ENPP5 ORF mammalian expression plasmid, Flag tag||HG11519-M-F|
|Human ENPP5 ORF mammalian expression plasmid, N-Flag tag||HG11519-NF|
|Human ENPP5 ORF mammalian expression plasmid, N-His tag||HG11519-NH|
|Human ENPP5 ORF mammalian expression plasmid, N-Myc tag||HG11519-NM|
|Human ENPP5 ORF mammalian expression plasmid, N-HA tag||HG11519-NY|
|Human ENPP5 natural ORF mammalian expression plasmid||HG11519-UT|
|Learn more about expression Vectors|
ENPP5 is a member of the nucleotide pyrophosphatase/phosphodiesterase family(NPP). It is a family comprised by dimeric enzymes that catalyze the hydrolysis of phosphate diester bonds. There are seven isoforms in NPP family, some of which prefer nucleotide substrates, some of which prefer phospholipid substrates, and others of which prefer substrates that have not yet been determined. NPP also belongs to the alkaline phosphatase (AP) superfamily of enzymes and they are located in the cell membrane and hydrolyze extracellular phosphate diesters to affect a wide variety of biological processes. ENPP5 belongs to a group of nucleotidemetabolizing ectoenzymes, which regulate the availability of extracellular nucleotides. ENPP5 may play a role in neuronal cell communication. Hhowever, it lacks nucleotide pyrophosphatase and lysopholipase D activity. It may also be involved in neuronal cell communication. The amino acid sequence of human ENPP5 is 100%, 88%, and 82% identical to that of chimpanzee, dog and mouse/rat. ENPP5 functions in phospholipid metabolism.