|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human PIGR ORF mammalian expression plasmid, C-GFPSpark tag||HG10131-ACG|
|Human PIGR ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10131-ACR|
|Human PIGR ORF mammalian expression plasmid, C-Flag tag||HG10131-CF|
|Human PIGR ORF mammalian expression plasmid, C-His tag||HG10131-CH|
|Human PIGR ORF mammalian expression plasmid, C-Myc tag||HG10131-CM|
|Human PIGR ORF mammalian expression plasmid, C-HA tag||HG10131-CY|
|Human PIGR Gene cDNA clone plasmid||HG10131-M|
|Human PIGR natural ORF mammalian expression plasmid||HG10131-M-N|
|Human PIGR ORF mammalian expression plasmid, N-Flag tag||HG10131-NF|
|Human PIGR ORF mammalian expression plasmid, N-His tag||HG10131-NH|
|Human PIGR ORF mammalian expression plasmid, N-Myc tag||HG10131-NM|
|Human PIGR ORF mammalian expression plasmid, N-HA tag||HG10131-NY|
|Human PIGR natural ORF mammalian expression plasmid||HG10131-UT|
|Learn more about expression Vectors|
Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.