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Rat CDH13 / Cadherin-13 / H Cadherin Protein

DatasheetSpecific ReferencesReviewsRelated ProductsProtocols
Rat CDH13 Protein Product Information
Protein Construction:A DNA sequence encoding the rat CDH13 (NP_620244.1)(Met1-Ala692) was expressed with six amino acids (LEVLFQ) at the C-terminus.
Expressed Host:Human Cells
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Rat CDH13 Protein QC Testing
Purity:> 90 % as determined by SDS-PAGE
Endotoxin:< 1.0 EU per μg of the protein as determined by the LAL method
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Ala 22
Molecule Mass:The recombinant rat CDH13 comprises 678 amino acids and predicts a molecular mass of 74.3 kDa. The apparent molecular mass of the recombinant protein is approximately 84-96 kDa in SDS-PAGE under reducing conditions.
Formulation:Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Rat CDH13 Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Rat CDH13 Protein SDS-PAGE
Rat CDH13 / Cadherin-13 / H Cadherin Protein SDS-PAGE
Other CDH13 Recombinant Protein Products
CDH13 / Cadherin-13 / H Cadherin Background

CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer.

Rat CDH13 / Cadherin-13 / H Cadherin References
  • Hart AB. et al., 2012, PLoS One. 7 (8): e42646.
  • Xu J. et al., 2012, BMC Cancer. 12: 243.
  • Jo J. et al., 2012, Obesity (Silver Spring). 20 (8): 1683-7.
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    Size / Price
    Catalog: 80280-RCCH-50
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