|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human FUT8 ORF mammalian expression plasmid, C-GFPSpark tag||HG11326-ACG|
|Human FUT8 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11326-ACR|
|Human FUT8 ORF mammalian expression plasmid, C-Flag tag||HG11326-CF|
|Human FUT8 ORF mammalian expression plasmid, C-His tag||HG11326-CH|
|Human FUT8 ORF mammalian expression plasmid, C-Myc tag||HG11326-CM|
|Human FUT8 ORF mammalian expression plasmid, C-HA tag||HG11326-CY|
|Human FUT8 Gene cDNA clone plasmid||HG11326-M|
|Human FUT8 ORF mammalian expression plasmid, N-Flag tag||HG11326-NF|
|Human FUT8 ORF mammalian expression plasmid, N-His tag||HG11326-NH|
|Human FUT8 ORF mammalian expression plasmid, N-Myc tag||HG11326-NM|
|Human FUT8 ORF mammalian expression plasmid, N-HA tag||HG11326-NY|
|Human FUT8 natural ORF mammalian expression plasmid||HG11326-UT|
|Learn more about expression Vectors|
Human alpha (1,6) fucosyltransferase 8, also known as FUT8, is a member of the glycosyltransferase family. Fucosyltransferases are the enzymes transferring fucose from GDP-Fuc to Gal in an alpha1,2-linkage and to GlcNAc in alpha1,3-linkage, alpha1,4-linkage, or alpha1,6-linkage. All fucosyltransferases utilize the same nucleotide sugar, their specificity reside in the recognition of the acceptor and in the type of linkage formed. Fucosyltransferases share some common structural and catalytic features. On the basis of protein sequence similarities, these enzymes can be classified into four distinct families: (1) the alpha-2-fucosyltransferases, (2) the alpha-3-fucosyltransferases, (3) the mammalian alpha-6-fucosyltransferases, and (4) the bacterial alpha-6-fucosyltransferases. The alpha-3-fucosyltransferases constitute a distinct family as they lack the consensus peptide, but some regions display similarities with the alpha-2 and alpha-6-fucosyltranferases.