|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A myc tag is a polypeptide protein tag derived from the c-myc gene product that can be added to a protein using recombinant DNA technology. It can be used for affinity chromatography, then used to separate recombinant, overexpressed protein from wild type protein expressed by the host organism. It can also be used in the isolation of protein complexes with multiple subunits.
A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.
The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.
|Mouse CLEC3B ORF mammalian expression plasmid, C-GFPSpark tag||MG50700-ACG|
|Mouse CLEC3B ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50700-ACR|
|Mouse CLEC3B ORF mammalian expression plasmid, C-Flag tag||MG50700-CF|
|Mouse CLEC3B ORF mammalian expression plasmid, C-His tag||MG50700-CH|
|Mouse CLEC3B ORF mammalian expression plasmid, C-Myc tag||MG50700-CM|
|Mouse CLEC3B ORF mammalian expression plasmid, C-HA tag||MG50700-CY|
|Mouse CLEC3B Gene cDNA clone plasmid||MG50700-M|
|Mouse CLEC3B ORF mammalian expression plasmid, N-Flag tag||MG50700-NF|
|Mouse CLEC3B ORF mammalian expression plasmid, N-His tag||MG50700-NH|
|Mouse CLEC3B ORF mammalian expression plasmid, N-Myc tag||MG50700-NM|
|Mouse CLEC3B ORF mammalian expression plasmid, N-HA tag||MG50700-NY|
|Mouse CLEC3B natural ORF mammalian expression plasmid||MG50700-UT|
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Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes via binding to plasminogen. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. Tetranectin may play a role in the wound healing process. Tetranectin may play a role in neurological diseases and may serve as a diagnostic aid in multiple sclerosis (MS). Tetranectin was found significantly under-expressed in both serum and saliva of metastatic oral squamous cell carcinoma (OSCC) compared to primary OSCC. Tetranectin is thought to enhance proteolytic processes enabling tumor cells to invade and metastasize.