|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive ,Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
A myc tag is a polypeptide protein tag derived from the c-myc gene product that can be added to a protein using recombinant DNA technology. It can be used for affinity chromatography, then used to separate recombinant, overexpressed protein from wild type protein expressed by the host organism. It can also be used in the isolation of protein complexes with multiple subunits.
A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.
The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.
|Mouse FLT4 ORF mammalian expression plasmid, C-GFPSpark tag||MG50584-ACG|
|Mouse FLT4 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||MG50584-ACR|
|Mouse FLT4 ORF mammalian expression plasmid, C-Flag tag||MG50584-CF|
|Mouse FLT4 ORF mammalian expression plasmid, C-His tag||MG50584-CH|
|Mouse FLT4 ORF mammalian expression plasmid, C-Myc tag||MG50584-CM|
|Mouse FLT4 ORF mammalian expression plasmid, C-HA tag||MG50584-CY|
|Mouse FLT4 Gene cDNA clone plasmid||MG50584-M|
|Mouse FLT4 ORF mammalian expression plasmid, N-Flag tag||MG50584-NF|
|Mouse FLT4 ORF mammalian expression plasmid, N-His tag||MG50584-NH|
|Mouse FLT4 ORF mammalian expression plasmid, N-Myc tag||MG50584-NM|
|Mouse FLT4 ORF mammalian expression plasmid, N-HA tag||MG50584-NY|
|Mouse FLT4 natural ORF mammalian expression plasmid||MG50584-UT|
|Learn more about expression Vectors|
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.