|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human REG4 ORF mammalian expression plasmid, C-GFPSpark tag||HG11186-ACG|
|Human REG4 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG11186-ACR|
|Human REG4 ORF mammalian expression plasmid, C-Flag tag||HG11186-CF|
|Human REG4 ORF mammalian expression plasmid, C-His tag||HG11186-CH|
|Human REG4 ORF mammalian expression plasmid, C-Myc tag||HG11186-CM|
|Human REG4 ORF mammalian expression plasmid, C-HA tag||HG11186-CY|
|Human REG4 Gene cDNA clone plasmid||HG11186-M|
|Human REG4 ORF mammalian expression plasmid, Flag tag||HG11186-M-F|
|Human REG4 natural ORF mammalian expression plasmid||HG11186-M-N|
|Human REG4 ORF mammalian expression plasmid, N-Flag tag||HG11186-NF|
|Human REG4 ORF mammalian expression plasmid, N-His tag||HG11186-NH|
|Human REG4 ORF mammalian expression plasmid, N-Myc tag||HG11186-NM|
|Human REG4 ORF mammalian expression plasmid, N-HA tag||HG11186-NY|
|Human REG4 natural ORF mammalian expression plasmid||HG11186-UT|
|Learn more about expression Vectors|
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.