|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human SERPINA7 ORF mammalian expression plasmid, C-GFPSpark tag||HG10993-ACG|
|Human SERPINA7 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10993-ACR|
|Human SERPINA7 ORF mammalian expression plasmid, C-Flag tag||HG10993-CF|
|Human SERPINA7 ORF mammalian expression plasmid, C-His tag||HG10993-CH|
|Human SERPINA7 ORF mammalian expression plasmid, C-Myc tag||HG10993-CM|
|Human SERPINA7 ORF mammalian expression plasmid, C-HA tag||HG10993-CY|
|Human SERPINA7 Gene cDNA clone plasmid||HG10993-M|
|Human SERPINA7 ORF mammalian expression plasmid, N-Flag tag||HG10993-NF|
|Human SERPINA7 ORF mammalian expression plasmid, N-His tag||HG10993-NH|
|Human SERPINA7 ORF mammalian expression plasmid, N-Myc tag||HG10993-NM|
|Human SERPINA7 ORF mammalian expression plasmid, N-HA tag||HG10993-NY|
|Human SERPINA7 natural ORF mammalian expression plasmid||HG10993-UT|
|Learn more about expression Vectors|
Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein which belongs to the serpin family. TBG is synthesized primarily in the liver as a 54 kDa protein.TBG is genomically a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG binds thyroid hormone in circulation. It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3’-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 and T3, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone.