|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Human FGFBP3 ORF mammalian expression plasmid, C-GFPSpark tag||HG10986-ACG|
|Human FGFBP3 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||HG10986-ACR|
|Human FGFBP3 ORF mammalian expression plasmid, C-Flag tag||HG10986-CF|
|Human FGFBP3 ORF mammalian expression plasmid, C-His tag||HG10986-CH|
|Human FGFBP3 ORF mammalian expression plasmid, C-Myc tag||HG10986-CM|
|Human FGFBP3 ORF mammalian expression plasmid, C-HA tag||HG10986-CY|
|Human FGFBP3 Gene cDNA clone plasmid||HG10986-M|
|Human FGFBP3 ORF mammalian expression plasmid, N-Flag tag||HG10986-NF|
|Human FGFBP3 ORF mammalian expression plasmid, N-His tag||HG10986-NH|
|Human FGFBP3 ORF mammalian expression plasmid, N-Myc tag||HG10986-NM|
|Human FGFBP3 ORF mammalian expression plasmid, N-HA tag||HG10986-NY|
|Human FGFBP3 natural ORF mammalian expression plasmid||HG10986-UT|
|Learn more about expression Vectors|
FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are important regulators of cell migration, proliferation and differentiation, e.g., during embryogenesis and wound healing, and under several pathological conditions including tumor growth and tumor angiogenesis. Expression of FGF-BP increases after injury to murine and human skin, in particular in keratinocytes. This upregulation is most likely achieved by major keratinocyte mitogens present at the wound site. FGFBP3 is a positive regulator of fibroblast growth factor receptor signaling pathway and vascular permeability. It interacts with 2,3,7,8-tetrachlorodibenzodioxine, benzopyrene and valproic acid. FGFBP3 also exhibits fibroblast growth factor binding (orthology) and heparin binding (orthology).