|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Canine FGF21 ORF mammalian expression plasmid, C-GFPSpark tag||DG70038-ACG|
|Canine FGF21 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||DG70038-ACR|
|Canine FGF21 ORF mammalian expression plasmid, C-Flag tag||DG70038-CF|
|Canine FGF21 ORF mammalian expression plasmid, C-His tag||DG70038-CH|
|Canine FGF21 ORF mammalian expression plasmid, C-Myc tag||DG70038-CM|
|Canine FGF21 ORF mammalian expression plasmid, C-HA tag||DG70038-CY|
|Canine FGF21 Gene cDNA clone plasmid||DG70038-G|
|Canine FGF21 ORF mammalian expression plasmid, N-Flag tag||DG70038-NF|
|Canine FGF21 ORF mammalian expression plasmid, N-His tag||DG70038-NH|
|Canine FGF21 ORF mammalian expression plasmid, N-Myc tag||DG70038-NM|
|Canine FGF21 ORF mammalian expression plasmid, N-HA tag||DG70038-NY|
|Canine FGF21 natural ORF mammalian expression plasmid||DG70038-UT|
|Learn more about expression Vectors|
Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes.