|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Canine BDNF ORF mammalian expression plasmid, C-GFPSpark tag||DG70029-ACG|
|Canine BDNF ORF mammalian expression plasmid, C-OFPSpark / RFP tag||DG70029-ACR|
|Canine BDNF ORF mammalian expression plasmid, C-Flag tag||DG70029-CF|
|Canine BDNF ORF mammalian expression plasmid, C-His tag||DG70029-CH|
|Canine BDNF ORF mammalian expression plasmid, C-Myc tag||DG70029-CM|
|Canine BDNF ORF mammalian expression plasmid, C-HA tag||DG70029-CY|
|Canine BDNF Gene cDNA clone plasmid||DG70029-G|
|Canine BDNF ORF mammalian expression plasmid, N-Flag tag||DG70029-NF|
|Canine BDNF ORF mammalian expression plasmid, N-His tag||DG70029-NH|
|Canine BDNF ORF mammalian expression plasmid, N-Myc tag||DG70029-NM|
|Canine BDNF ORF mammalian expression plasmid, N-HA tag||DG70029-NY|
|Canine BDNF natural ORF mammalian expression plasmid||DG70029-UT|
|Learn more about expression Vectors|
BDNF is a member of the nerve growth factor family. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It functions as the major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.