|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Canine NGF ORF mammalian expression plasmid, C-GFPSpark tag||DG70027-ACG|
|Canine NGF ORF mammalian expression plasmid, C-OFPSpark / RFP tag||DG70027-ACR|
|Canine NGF ORF mammalian expression plasmid, C-Flag tag||DG70027-CF|
|Canine NGF ORF mammalian expression plasmid, C-His tag||DG70027-CH|
|Canine NGF ORF mammalian expression plasmid, C-Myc tag||DG70027-CM|
|Canine NGF ORF mammalian expression plasmid, C-HA tag||DG70027-CY|
|Canine NGF Gene cDNA clone plasmid||DG70027-G|
|Canine NGF ORF mammalian expression plasmid, N-Flag tag||DG70027-NF|
|Canine NGF ORF mammalian expression plasmid, N-His tag||DG70027-NH|
|Canine NGF ORF mammalian expression plasmid, N-Myc tag||DG70027-NM|
|Canine NGF ORF mammalian expression plasmid, N-HA tag||DG70027-NY|
|Canine NGF natural ORF mammalian expression plasmid||DG70027-UT|
|Learn more about expression Vectors|
Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. In addition, previous studies indicated that NGF may also have an important role in the regulation of the immune system.