|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Canine IL1B ORF mammalian expression plasmid, C-GFPSpark tag||DG70018-ACG|
|Canine IL1B ORF mammalian expression plasmid, C-OFPSpark / RFP tag||DG70018-ACR|
|Canine IL1B ORF mammalian expression plasmid, C-Flag tag||DG70018-CF|
|Canine IL1B ORF mammalian expression plasmid, C-His tag||DG70018-CH|
|Canine IL1B ORF mammalian expression plasmid, C-Myc tag||DG70018-CM|
|Canine IL1B ORF mammalian expression plasmid, C-HA tag||DG70018-CY|
|Canine IL1B Gene cDNA clone plasmid||DG70018-G|
|Canine IL1B ORF mammalian expression plasmid, N-Flag tag||DG70018-NF|
|Canine IL1B ORF mammalian expression plasmid, N-His tag||DG70018-NH|
|Canine IL1B ORF mammalian expression plasmid, N-Myc tag||DG70018-NM|
|Canine IL1B ORF mammalian expression plasmid, N-HA tag||DG70018-NY|
|Canine IL1B natural ORF mammalian expression plasmid||DG70018-UT|
|Learn more about expression Vectors|
Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).