|Datasheet||Specific References||Reviews||Related Products||Protocols|
|Vector Type||Mammalian Expression Vector|
|Expression Method||Constiutive, Stable / Transient|
|Selection In Mammalian Cells||Hygromycin|
Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.
The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.
|Canine CAR9 ORF mammalian expression plasmid, C-GFPSpark tag||DG70002-ACG|
|Canine CAR9 ORF mammalian expression plasmid, C-OFPSpark / RFP tag||DG70002-ACR|
|Canine CAR9 ORF mammalian expression plasmid, C-Flag tag||DG70002-CF|
|Canine CAR9 ORF mammalian expression plasmid, C-His tag||DG70002-CH|
|Canine CAR9 ORF mammalian expression plasmid, C-Myc tag||DG70002-CM|
|Canine CAR9 ORF mammalian expression plasmid, C-HA tag||DG70002-CY|
|Canine CAR9 Gene cDNA clone plasmid||DG70002-G|
|Canine CAR9 ORF mammalian expression plasmid, N-Flag tag||DG70002-NF|
|Canine CAR9 ORF mammalian expression plasmid, N-His tag||DG70002-NH|
|Canine CAR9 ORF mammalian expression plasmid, N-Myc tag||DG70002-NM|
|Canine CAR9 ORF mammalian expression plasmid, N-HA tag||DG70002-NY|
|Canine CAR9 natural ORF mammalian expression plasmid||DG70002-UT|
|Learn more about expression Vectors|
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.